I go wired only. It only takes a tiny bit of care to make the wire all but invisible, and they're more reliable, cheaper, and the batteries last longer.
But I only have it there for speed/time. If I were doing cadence I might care more about wires. As is, you can only really see the wires a little on the front, and up there it's a forest of brake and shifter cables and headlight cable anyway, the comp sensor wire isn't even really noticeable.
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Work: the 8 hours that separates bike rides.