Originally Posted by Doug64

I always remove the factory lube, just for the reason you stated. I generally put the new chain into a small jar (we always have a lot peanut butter jars, but a plastic soda bottle will also work) with a small amount of degreaser, and give it a good shaking. I then do the same thing with hot soapy water, dish detergent, and shake again. The last step is a good rinse under hot water, and hang to dry. If I am in a hurry I use a hair drier to speed up the drying.

IME I get good chain life and the chains are easier to keep clean. I always put a new chain on before any long tour, which for us is annually.