A Giant Toughroad would be comfortable due to larger 50mm tires and CF fork.
As for the comment that hybrids are not worth upgrading.... well, technically no bike is if you look at it economically. My toughroad ended up with new DT Swiss wheels with wider rims, new tires, Brooks saddle, jones bar, XT 1x11 drivetrain, jones bar, custom frame bag..... I realize it all may not be economical, but it rides perfectly, is fun and is my road, gravel and hybrid bike.... all 3 in one single bike.