To be more accurate, the problem I see for the size of the Helix frame are (if those value are still valid for the production bikes):
- B) Effective top tube length: 590 mm / 23.2 in
- L) Frame reach: 435 mm / 17.1 in
Since he frame size is fixed, the only solution for that is to use another stem (like the sport stem of the Birdy) or another type of handlebar like a a race dropbar or a riser instead of a flatbar. but I think hat this will have a negative impact on the folded size.
For the ride performances, yes, on soft surface, bigger wheels help.
But on bad hard roads like cobbles, they do not really help. With as consequence a lack of comfort and for very bad roads being forced to ride slower.