Could you provide links to the exact bikes? Unless I'm looking at the wrong bikes, there's a huge price difference between the two so I'm not even sure why they're being compared. The
Cannondale with Ultegra is a disc model with carbon wheels where as the
Canyon is a rim-brake model for $1,700 less. Money aside, I'd go with the Cannondale because I'm completely sold on disc brakes and feel they're more "future proof". But for $4,200, there's a bunch of bikes that could/should be considered.