I’d say people sometimes overestimate the difference in weight distribution because they don’t consider the weight distribution during braking nor while standing out of the saddle. I prefer to run the front pressure no more than 10% below the rear. So I just run similar tire sizes.
OTOH, it will totally work to run different sizes front and rear. It accomplishes different things depending on where you put the larger tire. Larger tire in back and you could run pressures the same, and probably is more efficient. Larger tire in front means lower pressure and maybe easier on your hands.
Otto