Yes its worth it, as already mentioned, if it fits. I'd check for chain stretch so see if you're looking at repairs right from the beginning. The 10sp Dura Ace this came with is a nice, smooth shifting, and reliable components group. Although 11 and 12 speeds are nice, 10sp isn't really lacking for much, and 10sp DA isn't slowing you down. The wheels aren't that special and weren't very high end at their time but still smooth and reliable. If something goes wrong with them nice 10sp road wheels are plentiful thanks to all new standards. Wouldn't want to guarantee anything but I don't recall many bikes from the early 2000s being unable to handle 25c, though sometimes I feel like 25c tires at the time were slightly narrower than they are today. Plenty couldn't handle bigger but 25c was a fairly common road size by 2006.