I bought my first bike with STI/"brifters" over 20 years ago, have never missed the old separate shifters/levers. My multi-day touring is never longer than 4 or 5 days - I know long distance tourers still prefer the bar end or even down tube shifters for simplicity and fix-ability, but in those 20 years and three bikes with integrated, I've never had a failure. For 99.99% of my riding, having my hands near both the brakes and the shifters when riding on the hoods or the drops has been a big gain in my ability to quickly react.