A bicycle is a highly personal machine. It has to fit your body perfectly for your comfort and long term enjoyment. And to achieve such state of affairs requires time and effort. For most of us, there was no "perfect" bike from the get go. Back in the day, we had to make changes and add other items to make our rides more comfortable and enjoyable. Today, there are countless different models and frame sizes/shapes to choose from. That is great because now you can at least find a rather more fitting canvas to work on.
So when people argue about "which setup is the best", i am sorry but it is just babble. "Whatever floats your boat" should be the normal thing to say.