There could be many reasons why a saddle is uncomfortable that have little to do with the saddle itself including how one sits on that saddle due to a poor fit. For myself, after many painful miles where, at one point, I thought about giving up on cycling I discovered the saddle shape that works for me. Unfortunately no one makes that saddle so I've taken to modifying saddles with a heat gun. Most saddles have a triangular shape as viewed from above with the result that they are way too wide just forward of the widest point under the sit bones. That is the area I remold with heat making it narrower. I also like a cutout. The result of this customizing is a saddle I am comfortable on all day.