Originally Posted by Sy Reene

You can.. but tricky to keep 4-5 different powders evenly mixed together in the proportions you want over time.. finer/denser grains will settle, etc.

A standard bike water bottle is typically 22ozs.. so your calculations equate to roughly 11-12 cents per bike bottle (vs Gatorade powder coming in at 20 cents). If this is worth it to you then by all means give it a shot.