Left knee has been a problem this year, but last year's saddle sore was not. Doc says MRI says, 'It's worn out.' But luckily, the pain is way less than would justify surgery, IMO.
Last week I noticed my natural foot placement was about a half inch from the inside edge of my pedals, so I ordered some pedal extenders. Last week I also noticed my saddle was pointing NNW instead of N, and I remembered I had done that to reduce pressure on the sore. No sore, so I swiveled it back so it was straight. I did this about 8 miles into what became a 22 mile ride. I rode a lot stronger after the change than before it ... and my symptoms changed.
Now my right knee hurts a bit while riding. My left knee, which previously hurt only on the bike, now hurt off the bike, too, sometimes. And the sore started coming back.
But, hell, I rode stronger. Install the pedal extenders. Cue the Body Glide. Cue the ibuprofen before the ride. Cue ice after the ride. Cue the PT.
Wish me luck.