Originally Posted by
randallr
My wife has similar, probably not as advanced as what you describe, couldn't work cables to her SRAM shifters due to finger strength/pain issues, we put her on Shimano Deore Di2 1x (retrofitted her Domane with that) and it helped a lot. Bike fitter also got her into more upright position with different stem and bars.
More practical option if you want lightweight. The Alfine and coaster brakes, are no lighter weight than the Dutch bike you have now. Disc brakes of the hydraulic type might be easier for our poster's wife to operate.