There's no best. There are considerations and various solutions that address them.
The 2:1 pattern you seem to favor does help address the effects of dish, but calls for z heavier stiffer rim to handle the longer spans between bracing points. Switching it as you propose has been done, but means that driving torque has to be carried across the hub shell and therefore a heavier stiffer hub.
An alternate, simpler way is to reduce the gauge of the spokes rather than the number. This addresses the dish question without increasing stresses on the rim and hub.
Of course mixed gauges aren't visibly obvious, and 32 or 28h wheels lack the cool factor that marketers need to get folks to buy more stuff, even when what they have is still OK.
__________________
FB
Chain-L site
An ounce of diagnosis is worth a pound of cure.
Just because I'm tired of arguing, doesn't mean you're right.
“One accurate measurement is worth a thousand expert opinions” - Adm Grace Murray Hopper - USN
WARNING, I'm from New York. Thin skinned people should maintain safe distance.