I would go tubeless but bring spare tubes. Keep the sealant fresh, and hopefully you won't need the tubes, but if you do need them, you have them, and you can convert to a tube set-up when necessary.
No idea how to carry a laptop on a bikepacking set up. My iPad sits in my handlebar bag, but that likely won't work for a laptop. Backpack would work, but I'd rather use a rear rack than a backpack.