NOS, have you tracked down what caused the ITB issue in the first place?
I had it chronically for about a year, and exacerbated it when pushing hard at low cadence (generally while touring, but also on a highly geared road bike).
I also fiddled with the Q on my cranks a little -- using MTB cranks means one side can be further away from the seat tube or centreline than the other. Cleats weren't an issue because I was using Time Atac with generous float. However, I also trimmed away a small section of the sole of my shoe so that I could clip out more easily -- the rubber was fouling the springs in the pedals and I had to use more than usual force to twist out the cleat, and that was a big problem for me late in a 600km randonnee when I almost fell off the bike trying to unclip.
Those changes along with riding at higher cadences, lower gears up hills with loads and using a stretch helped overcome the issue.
I get an occasional twinge, and this more so now I have gone to Shimano pedals (but with the 3-degree float).; I've recently rotated the cleat on one of my new pair of shoes to help solve that twinge.