Saddle sores are a fact of life if you ride high mileage. I keep them clean and mix a triple antibiotic with cortisone cream rubbed into them. I also use a product that I get at Dick’s Sporting Goods called “Body glide” as a lubricant applied before the ride. My last ride was 72 miles with 5,000 feet of ascent (we have hills here). On hill is 2.3 miles long at 12%. Many more hills are 10% and long. I also go to sales at the end of the cycling season and buy a bunch of bib shorts at half price so I can throw away the ones that are worn.