I grew up in New Orleans. The best way to cross the Mississippi was the Canal Street Ferry. It gives you great views of the city and the French quarter.
https://www.neworleans.com/plan/tran...algiers-ferry/
I visited L. Itasca when I rode across the US on the Adventure Cyclist northern tier. For a New Orleans boy, it sure was fun walking across the Mississippi River.
I live in central Iowa now and I enjoy checking out all the river towns in the eastern part of the state. Plus the driftless region (SW WI, SE MN, and NW IA) has great scenery, hiking, and biking. I'll have to check out the Centennial Bridge. Thanks to
jamawani for starting this thread.