Bicyclerollingresistance.com does rolling resistance tests on rollers with a bumpy surface, vs. the perfectly flat rollers that were long used. The theory is that this simulates a more typical riding surface for everyone except velodrome racers! They also do testing at various speeds, not just 25 mph racing speeds.
That type of testing has shown that for most non-racers narrower and higher pressure does not always mean lower rolling resistance. In fact, for the speeds I go at and the roads I ride on, narrow tires at high pressure make no sense. At 15 - 18 mph average, the aero factors are minimal - and my gigantic body width swamps the contribution of the wheels in wind resistance by a huge margin anyway.
I agree with the earlier poster about flats - I'll spend a watt or two to reduce flatting on the road to near zero. BicycleRollingResistance also does puncture resistance testing.