Not much mention of wheels and their impact on the ride. However, in my experience, wheels & spokes, along with tires, have as much impact on ride quality as does the frame. Had an early set of the TOTL Ksyrium with 25s on a Ti frameset that was almost unrideable for anything but a criterium length ride. Felt every bump and crack and pebble on that horrible combination. Was better on lugged steel but they were soon gone to someone who was a sprinter. For me, the combo of lugged steel & Campy Sirocco wheels with 28s or 32s have proven most comfortable over the years (I'm 72 & counting). Speed is no longer an issue. I'll eventually get there......................