I have a stable that includes STI, bar-end friction, and even a bike with downtube friction shifters. Right now I can hop on any of them without having to acclimate in any major way to the feel of the shifting.
The stable you're contemplating is far less problematic than mine. A lot of people can hop on an unfamiliar integrated-shifting system for the first time, and largely get used to it within a matter of minutes. That's especially true for e-shifting, where your hand technique plays literally zero role in the derailleur actuation. Even if you have a harder time with it, and switching feels a bit strange at first, you can acclimate to acclimation: the more you do it, the less you'll notice the switch. It's very unlikely that you'll have trouble after a few switch cycles.