new setup
I may try the FSA 46/30 when it comes out, but I am building now a new bike with 11 spd Ultegra Di2 parts I have, but with a Praxis 48/32 up front and IRD 11-40 in the rear, using a Wolftooth Roadlink on the rear derailleur hanger. The gap in front of 16 is outside the nominal spec, but I think that I can get the chain length barely ok to permit accidental big/big gear combos with no destruction and with minimal dragging in an accidental small/small combo. I have been using 11/36 in the rear and 50/34 up front with the di2 mechs with no problem at all, so the new system just adds 2 effective teeth to the big/big combo. I will report how it works (or doesn't!).