Thread: Dexamethasone
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Old 06-23-20, 08:18 AM
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Comparing dexamethasone to non steroidal anti-inflammatory drugs, much less micronutrients with anti-inflammatory properties, is like comparing a tactical nuke to an M80.

Yes, dexamethasone has often been used as a "heroic," last ditch method in critically ill patients, e.g., with sepsis, experiencing overwhelming immune responses and multi-organ failure, and it has a very mixed reputation. The obvious and real danger is that suppressing the immune system removes the last remaining check on the infection, resulting in death.

It is wonderful to hear that this widely used and inexpensive drug is helpful in critically ill patients with COVID-19. This could turn out to be one of the few well-defined situations where it is helpful in critical illness. Or not. The critical care community has been disappointed many times before.
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