I'd agree that big frames tend to feel better when you ride them. My main concern is being able to get at least a toe down when I pull up at a junction, so that I don't up arse over tit in a heap in the road.
I'm not too fussed about stand-over height, as I would be in the middle of crashing if that were a concern, and I'd be more worried about bouncing my face off the scenery or other traffic in that scenario.