Originally Posted by
ksryder
Road shifters won't work with Shimano MTB derailleurs 10sp or above, different cable pull ratio. If you want Shimano 105 10speed (aka 5700) you'd need to get a 105 10sp RD.
I'm pretty sure wolftooth and a few others make pulleys that will let you use road shifters with em. Haven't tried that myself though.
Not too sure on brake compatibility wrt mech disc brakes on rd vs mtb since it hasn't been a concern for me.