After 100+ mile days, I would have numbness in my hands which would last for over a week. Purchased a Specialized road bike with Futureshock as well as started running larger 30mm tires tubeless with lower pressures and numbness is gone. I mention this not expecting someone to run out and purchase a new bike and wheels but to highlight equipment can help. I would start with new gloves which may suit your hands better, double wrap padded bar tape, larger supple tires with latex tubes running lower pressures ect.