I think it's always possible to screw it up. We have a ~65 y.o. ex-gym owner we see at the gym. He's big and has been working out all his life, has good form, etc. He popped a disc doing heavy deadlifts many years ago. His advice: don't do heavy lifts. Just don't. Sooner or later, you'll make a mistake and regret it the rest of your life. It's not worth it.
My research says that the exact weight doesn't matter, only the exhaustion. You can get about the same result from sets of 20 as sets of 5, as long as you take both to failure. But 20 is safer. That is unless you're competing, in which case you have to do what you have to do regardless of risk.
It's notable that studies of progress using 1 minute rests vs. 5 minute rests between sets found that the 5 minute people were able to use more weight, but also had more injuries. I use 1 minute rests.
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Results matter