Saddle height is far more relevant than an inseam measurement. I'm only 168cm tall, but my saddle height is 73cm. I look for a stack height of 520-530mm and a reach of 370-385mm. If you know what stack and reach are needed, it only takes seconds to find the right size. With my dimensions I would use 0-10mm of spacer and a -17 stem, with a 100-110mm length. I can always decide to raise the bars by about 2cm, just by using a -6 stem. That would produce an 8cm saddle to bar drop Instead of 10cm.
Trek's bikes seem to ignore riders with long legs. Even with the long mast, the saddle rail height maximum may be 68cm, which is too short. The next size up would barely have enough rail height.