My big ride prep includes a bedtime dose of magnesium, calcium, potassium, Move Free, Benadryl, melatonin and Ibuprofen with yogurt and a quart of water. This all helps with restorative sleep and inflammation from arthritis and shoulder tendonitis.
I also get out the foam roller to stretch the back, legs and I-bands.
Finally, all prep work on the bike and packing is done and check listed.