Monitoring CICO is important for sure, but there appears to be more to it than only that.
Consider studies of dieters. Most weight-loss schemes revolve around reducing the overall number of calories consumed – but what if the timing also determined the benefits? When overweight and obese women were put on a weight-loss diet for three months, those who consumed most of their calories at breakfast
lost two and a half times more weight than those who had a light breakfast and ate most of their calories at dinner –
even though they consumed the same number of calories overall.
BBC - Future - How meal timings affect your waistline