I rode Selle Italias, both under their name and other names for many years. Raced them, put many thousands of miles on them and loved them. (The Avocet II and IIIs were those saddles.) Then in my 40s, I changed and they no longer worked because of perineum issues. I now ride virtually the same saddle (I believe still made by Selle Italia), the Terry Fly that incorporates a cutout. Not always comfortable early in rides but as they go on and get harder, those seats are never an issue. And really hard rides? They are not even there. I cannot ask for more.
Ben