I have 16,000 miles on my Di2 so far. The ease of use with winter gloves on was touched upon earlier, but what hasn't been mentioned (that I saw) was the ability (with Di2 at least) to simply hold the up/down shift button/lever and dump the entire rear cassette in either direction with a single press and hold. This is a great feature if you do lots of really cold winter riding with your thickest gloves on, and possibly like me, also with silk liners on underneath the gloves, where it becomes nearly impossible to find and feel the shift lever through your gloves, especially when the fingers get cold and numb'ish, let alone press the lever 9-10 times in a row in a mech. shifting system, when going from little ring to big ring, or vice versa. With Di2, just hold and dump!