I had a 2001 Sienna that I drove for 14 years and 185k miles, and I bought it used. Never a problem until right near the end, and then it was fairly minor things like some sort of sticky O2 valve if I remember right. I started to trust it a little less for long trips so that's when it was time to go. Had that loaded with bikes, ski gear, camping gear, etc.. many times, not to mention a family of 4 + dog. Even more space for everything when I put a Yakima box on top.
Edit - my Sienna did have a full size spare.
Last edited by cmh; 03-12-21 at 10:16 AM.