I’m 220 lbs and run my 29’er Nobby Nics at 22 psi front, 25 rear, tubeless. Have had no pinch flats (or any flats) and no rim strikes. I’m not jumping this bike. I just experimented on a bunch of rides (using a digital gauge) and went to 20, then up to high 20’, finally settled on these numbers based on comfort and handling. This is easily 10-15 psi lower than what I ran on 26” x 2.2 tires.