Wow big john, that's a lot of tough news all at once.
It also sounds like a situation that could be turned around onto an opportunity to re-evaluate. Do you love where you live? Is there any where you always wanted to live or a career move your wife is interested in? Possibilities are very open right now, you could move, retrain, take a sabbatical (put your stuff in storage and ride your bike around the world)... Obviously if you have kids or parents to support or other obligations you can't walk away from them, but don't be trapped by having to have some life path that other people define.