Geekage

This is a complete system with hose and valve that, according to the seller, "can fill up 1 tire (700x25) from total flat to 100 PSI and will be left with little more air in"

So, that's a little more than an equivalent 16 gram cartridge in the size of a water bottle.

I'm not sure you really want that.

Many of the ideas about CO2 cartridges and refillability have already been addressed ad nauseum in the paintball world: refillable 12gr cartridges, larger bulk fill tanks (and necessary burst discs), etc.

re: how many cartridges? It really depends on the tire and cartridge. Look up "CO2 inflation chart" to get a rough idea. For example, a single 12gr co2 cartridge should get my 700x28c tires up to 60psi. Not my usual 70 psi but still more than I often let my tires drop to.