I was diagnosed with it ~20 years ago. Seemed to get worse for a couple years, then the size of the "nodules" reduced slightly, and it's remained fairly benign since then. A hand doctor i visited recently (for an unrelated issue) insisted that it was probably a misdiagnosis if the symptoms didn't get worse or improved. Anyway, it's never interfered with my cycling ...but there are plenty of other reasons I can think of for wearing padded gloves when riding.
btw, a friend of mine was also diagnosed with DC and didn't get off nearly as easily as I did: She just recently had extensive surgery and will be off the bike for a couple months.