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Addiction LXXVI

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Road Cycling It is by riding a bicycle that you learn the contours of a country best, since you have to sweat up the hills and coast down them. Thus you remember them as they actually are, while in a motor car only a high hill impresses you, and you have no such accurate remembrance of country you have driven through as you gain by riding a bicycle. -- Ernest Hemingway

Addiction LXXVI

Old 10-22-19, 04:10 PM
  #1026  
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Originally Posted by datlas View Post
One of our patients just dropped off TWO big boxes of fresh apple cider donuts.

I don't think you can ride off those calories, ever.
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Old 10-22-19, 04:41 PM
  #1027  
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Originally Posted by BillyD View Post
The question IS ... which one is worse for your liver.

I'm an Ibu guy, my system laughs at acetaminophen.
Neither.

Ibuprofen is simply not liver-toxic because it isn't metabolized there. It can cause kidney damage in overdoses or in the face of serious dehydration. However, the main risk is intestinal bleeding. There is a theoretical risk of accelerated atherosclerosis in chronic high dose use. People with bleeding problems shouldn't take it.

Acetaminophen will wipe out the liver with overdose, but if you don't have pre-existing liver disease, take liver-toxic meds, and aren't stressing your liver with booze, it is completely safe at recommended doses.

End of story.
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Old 10-22-19, 04:44 PM
  #1028  
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Originally Posted by BillyD View Post
My blood sugar spiked just looking at that.
Actually, looking at that can make your insulin spike and cause you to want sugar.
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Old 10-22-19, 04:45 PM
  #1029  
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Originally Posted by LesterOfPuppets View Post
I'm just having fig Newtons

And a quad shot latte
I like fig newtons.
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Old 10-22-19, 05:08 PM
  #1030  
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Originally Posted by rpenmanparker View Post
I dont like the liver implications of acetaminophen. So I pick a different poison. Ibuprofen or Naproxen! Im okay now. I hope it stays that way.
Acetaminophen is one of the only medicines one can say is 100% safe if you follow the directions. Not so with the others you listed. Believe me.
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Old 10-22-19, 05:31 PM
  #1031  
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Originally Posted by datlas View Post
Acetaminophen is one of the only medicines one can say is 100% safe if you follow the directions. Not so with the others you listed. Believe me.
Reading the instructions for most things are more important than many think. Especially meds. Having been the guy writing instructions for electrical machinery used in factories, I see how not reading them can be foolish, even dangerous, in some cases. Very annoying.

Last edited by 2manybikes; 10-22-19 at 05:56 PM. Reason: typo
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Old 10-22-19, 05:35 PM
  #1032  
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Originally Posted by BillyD View Post
The question IS ... which one is worse for your liver.

I'm an Ibu guy, my system laughs at acetaminophen.
Exactly. I have been recently impressed by how often Naproxen is prescribed for common conditions like prostatitis and orthopedic pain. The MDs really seem to like it instead of Celebrex and such.
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Old 10-22-19, 05:47 PM
  #1033  
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Originally Posted by rjones28 View Post
I like fig newtons.
Me too. But not enough protein alone for century plus rides.
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Old 10-22-19, 05:55 PM
  #1034  
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Originally Posted by BillyD View Post
Also I got a toothache now, too.
Now I feel fat.

And anyone that says "bummer" is ok with me.
I also learned at the bike shop today, jeans with holes in them look hot on the right female. I must be old.
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Old 10-22-19, 06:02 PM
  #1035  
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Originally Posted by rpenmanparker View Post
Exactly. I have been recently impressed by how often Naproxen is prescribed for common conditions like prostatitis and orthopedic pain. The MDs really seem to like it instead of Celebrex and such.
Celebrex has a Black Box Warning from the FDA for its cardiovascular risk. It and the other COX-2 inhibitor are to be avoided.
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Old 10-22-19, 06:20 PM
  #1036  
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Update: Got a snake-bite flat when I was riding on Sunday. I ran over a large, Chrome, truck-size lug nut. I limped home pumping up the air twice and just changed it tonight. I didn't have time on Sunday because we were going to dinner and I couldn't be late. removing the rear wheel was very easy perhaps the vertical dropouts on the new bike versus the horizontal ones on my old bike made it easier.

Yesterday I rode my old bike and it felt strange.

When I bought the new bike I asked if 28's would fit and they said yes however 25's are what are on the wheels now. I would assume the brake caliper is the limiting factor and not the wheel size. see attached pic. Thoughts? TIA.
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Old 10-22-19, 06:35 PM
  #1037  
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Originally Posted by DougRNS View Post
Update: Got a snake-bite flat when I was riding on Sunday. I ran over a large, Chrome, truck-size lug nut. I limped home pumping up the air twice and just changed it tonight. I didn't have time on Sunday because we were going to dinner and I couldn't be late. removing the rear wheel was very easy perhaps the vertical dropouts on the new bike versus the horizontal ones on my old bike made it easier.

Yesterday I rode my old bike and it felt strange.

When I bought the new bike I asked if 28's would fit and they said yes however 25's are what are on the wheels now. I would assume the brake caliper is the limiting factor and not the wheel size. see attached pic. Thoughts? TIA.
The rim is fine for 28s or 40s, for that matter. As you say, its the frame and the brake gap. If your 25s are decent quality and youre not a big palooka like WhyFi, Id ride them until the air shows through.
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Old 10-22-19, 06:45 PM
  #1038  
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Originally Posted by MoAlpha View Post
The rim is fine for 28s or 40s, for that matter. As you say, its the frame and the brake gap. If your 25s are decent quality and youre not a big palooka like WhyFi, Id ride them until the air shows through.
Don't go talking smack about @WhyFi's weight. He is getting svelte - @Trsnrtr svelte. You have my permission to talk smack about his non-marigold jacket that lacks awesomeness.

You must be new here. No way in hell am I taking the 25's off until cords are showing. When they do, and only then, I will buy 28's if I determine the clearance is adequate.

#SpoutingNonsense
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Old 10-22-19, 06:47 PM
  #1039  
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Originally Posted by MoAlpha View Post
Celebrex has a Black Box Warning from the FDA for its cardiovascular risk. It and the other COX-2 inhibitor are to be avoided.
The PRECISION study suggests its as safe (maybe even safer) than Naproxen or Ibuprofen.
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Old 10-22-19, 07:02 PM
  #1040  
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Originally Posted by datlas View Post
The PRECISION study suggests its as safe (maybe even safer) than Naproxen or Ibuprofen.
I am sure that study was funded by big pain reliever.

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Old 10-22-19, 07:18 PM
  #1041  
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Originally Posted by datlas View Post
The PRECISION study suggests it’s as safe (maybe even safer) than Naproxen or Ibuprofen.
Y’all listen to @datlas. Doesn’t reflect well on the NSAIDs as a class. I avoid all that ****.
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Old 10-22-19, 08:12 PM
  #1042  
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Originally Posted by MoAlpha View Post
The rim is fine for 28s or 40s, for that matter. As you say, its the frame and the brake gap. If your 25s are decent quality and youre not a big palooka like WhyFi, Id ride them until the air shows through.
I'll have you know that I'm closing in on medium palooka status.
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Old 10-22-19, 08:19 PM
  #1043  
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Originally Posted by rjones28 View Post
I like fig newtons.
I do too, but all this talk of artisanal goods makes the Newtons seem second rate.

#professionallymade
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Old 10-22-19, 08:22 PM
  #1044  
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Originally Posted by Trsnrtr View Post
Dishonored2 is great but I gave up on Deus Ex: Mankind Divided. The interface and all was clunky and cumbersome like they were trying to do too much with it. Maybe I'll try it again this Winter.
I picked up a new GPU yesterday and was going to install DX:MD... holy schnikes - 75gb install?! Pass for now - maybe if I pick up a new (larger) ssd on Black Friday.
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Old 10-22-19, 08:22 PM
  #1045  
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Originally Posted by DougRNS View Post
Update: Got a snake-bite flat when I was riding on Sunday. I ran over a large, Chrome, truck-size lug nut. I limped home pumping up the air twice and just changed it tonight. I didn't have time on Sunday because we were going to dinner and I couldn't be late. removing the rear wheel was very easy perhaps the vertical dropouts on the new bike versus the horizontal ones on my old bike made it easier.

Yesterday I rode my old bike and it felt strange.

When I bought the new bike I asked if 28's would fit and they said yes however 25's are what are on the wheels now. I would assume the brake caliper is the limiting factor and not the wheel size. see attached pic. Thoughts? TIA.
Rim strip information has essentially no bearing on tyre width considerations, IMO.
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Old 10-22-19, 09:42 PM
  #1046  
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Originally Posted by rjones28 View Post
Congrats!
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Old 10-23-19, 05:30 AM
  #1047  
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Originally Posted by rjones28 View Post
I like fig newtons.
I often pick some up while touring. They are both filling and light. I also like Strawberry Newtons.
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Old 10-23-19, 05:50 AM
  #1048  
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Originally Posted by WhyFi View Post
I'll have you know that I'm closing in on medium palooka status.
Right on, Bro.
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Old 10-23-19, 06:26 AM
  #1049  
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Originally Posted by MoAlpha View Post
Neither.

Ibuprofen is simply not liver-toxic because it isn't metabolized there. It can cause kidney damage in overdoses or in the face of serious dehydration. However, the main risk is intestinal bleeding. There is a theoretical risk of accelerated atherosclerosis in chronic high dose use. People with bleeding problems shouldn't take it.

Acetaminophen will wipe out the liver with overdose, but if you don't have pre-existing liver disease, take liver-toxic meds, and aren't stressing your liver with booze, it is completely safe at recommended doses.

End of story.
Let me rephrase that - which one has the most potential for harm to ones body or overall wellness?

And in my experience the story is never over, there are always new studies being done with new findings challenging old doctrine. Im always concerned whenever I ingest any product from Big Pharm, theres nothing they wont do for a buck.

#callmecynical
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Old 10-23-19, 07:01 AM
  #1050  
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Originally Posted by BillyD View Post
Let me rephrase that - which one has the most potential for harm to one’s body or overall wellness?

And in my experience the story is never over, there are always new studies being done with new findings challenging old doctrine. I’m always concerned whenever I ingest any product from Big Pharm, there’s nothing they won’t do for a buck.

#callmecynical
I agree with your take and acetaminophen is unquestionably your man. Any bad effects of acetaminophen which took this long to be detectable would be massively outweighed by the known risks of NSAIDs. All this stuff is off patent, anyway, so Big Pharma doesn't care.
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