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Originally Posted by genejockey
(Post 22289944)
Ran out of Marker Mark Bourbon and had to depend on Jack Daniels Rye. But they're real Luxardo Marasco cherries, not the fake colored supermarket maraschino sort.
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Velo Vol
Here is where it started. Mo was talking about the booster and you said another one every 6 months. Meaning a second booster which no one has had. A first booster yes but those were first available in ~ September. https://cimg4.ibsrv.net/gimg/bikefor...4dbf4320d7.jpg |
Originally Posted by Velo Vol
(Post 22289965)
I don't accept that it's a "hypothetical" that people get COVID shots every six months when we've had at least two people here who have already done so.
But it's important to remember that reality requires neither your acceptance nor your comprehension. |
Originally Posted by LesterOfPuppets
(Post 22289979)
I don't think I've had Maker's since the turn of the century, maybe I should get a bottle for egg nog season.
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Originally Posted by DougRNS
(Post 22289992)
Velo Vol
Here is where it started. Mo was talking about the booster and you said another one every 6 months. Meaning a second booster which no one has had. A first booster yes but those were first available in ~ September. |
Originally Posted by DougRNS
(Post 22289891)
Do you play one on TV or the internets?
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Originally Posted by Velo Vol
(Post 22290035)
Whatever a frequent cycle turns out to be--six months, twelve months--it doesn't matter. The question is about the bodies' reaction to subsequent injections.
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Originally Posted by genejockey
(Post 22289509)
It depends on how light the room is otherwise. If there are lots of south-facing windows, you can get away with darker, but if it's facing north, or not too many windows, no.
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body’s
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Originally Posted by genejockey
(Post 22289944)
Ran out of Marker Mark Bourbon and had to depend on Jack Daniels Rye. But they're real Luxardo Marasco cherries, not the fake colored supermarket maraschino sort.
Originally Posted by LesterOfPuppets
(Post 22289979)
I don't think I've had Maker's since the turn of the century, maybe I should get a bottle for egg nog season.
https://cimg4.ibsrv.net/gimg/bikefor...cb9d731441.png It's for sipping though, not mixing. Grab some Evan Williams or something for mixing. |
Originally Posted by genejockey
(Post 22290025)
I find the 'dip' cheesy, but the booze inside is decent. Probably go for Bulleit next time.
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Originally Posted by WhyFi
(Post 22290069)
Sometimes language seems so horribly inadequate. If only there was a concise way to communicate the notion that something is currently unknown but that there's reason to suspect that some outcomes are more probable than others... :foo:
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Originally Posted by DougRNS
(Post 22289925)
1 nosebleed seat costs 20 times today's meal for two. NFW.
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Originally Posted by genejockey
(Post 22289905)
The best part of a Manhattan is the cherry, if you're using
Although I do enjoy the cherry. |
Originally Posted by genejockey
(Post 22289946)
You mean you won't accept 40 years of experience in BioPharma, most of it in infectious disease, and most of that in vaccinology?
You think MD's know this stuff? That's not how they're trained. |
Originally Posted by genejockey
(Post 22289905)
The best part of a Manhattan is the cherry, if you're using good cherries.
(the identity of the guest vocalist surprised me when I got the record BITD) |
Originally Posted by genejockey
(Post 22289549)
I do not understand the stylistic swings in home decoration these days. I have seen a number of houses, in my search for a place to retire, where I was convinced the pictures were shot in black and white, until I noticed some color outside the windows.
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Originally Posted by LAJ
(Post 22289953)
Butternut squash. The crust looks killer though.
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Originally Posted by BillyD
(Post 22290085)
body’s
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Originally Posted by BillyD
(Post 22290127)
Hmmmmm. Just a wild stab in the dark to consider, but maybe we should call that, ummm . . . . . . a hypothesis.
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All dressed up and no place to go. The phone appeared to be plugged in but was not. Sad!
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Originally Posted by seedsbelize2
(Post 22290199)
Miss the Penman
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Originally Posted by indyfabz
(Post 22290194)
And two cheeses and onion and chard and garlic and red pepper flakes and thyme and sage. I cheated by using pre-cut squash from TJ’s.
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Originally Posted by seedsbelize2
(Post 22290199)
Miss the Penman
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Originally Posted by BillyD
(Post 22290239)
He was an excellent debater. You could have a disagreement with him without feeling like it's an argument or a fight.
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Originally Posted by LAJ
(Post 22290214)
Yep. I'm guessing the cheese and seasonings covered up the squash taste well enough to enjoy it. I'm just not a squash fan. It did look good though.
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Originally Posted by indyfabz
(Post 22290281)
I was just thinking about him the other day. Where did he go?
Edit: https://www.bikeforums.net/road-cycl...xviii-348.html |
Perfect morning for a ride - sunny and 55-65. Even some proper cattle. https://cimg5.ibsrv.net/gimg/bikefor...0320db99e1.jpg https://cimg0.ibsrv.net/gimg/bikefor...47ce061052.jpg https://cimg3.ibsrv.net/gimg/bikefor...59e756d7ec.jpg |
Originally Posted by Velo Vol
(Post 22290035)
Whatever a frequent cycle turns out to be--six months, twelve months--it doesn't matter. The question is about the bodies' reaction to subsequent injections.
We don't even know that there will be a need for more than a third shot. Most pediatric vaccines, there are several shots in the first couple years and none after that, but the protection lasts. And no, response doesn't diminish with subsequent vaccinations. It increases. That's why they do them that way. When we immunize mice to generate antibodies, we do it repeatedly over a number of weeks, and the antibody titer increases, and the antibodies being produced increase in affinity as the B-cells undergo somatic mutation, affinity maturation, and class switching. |
Originally Posted by genejockey
(Post 22290316)
Which is why it's a hypothetical, because it's not possible to answer it yet. We'll know more in about 5 months.
We don't even know that there will be a need for more than a third shot. Most pediatric vaccines, there are several shots in the first couple years and none after that, but the protection lasts. And no, response doesn't diminish with subsequent vaccinations. It increases. That's why they do them that way. When we immunize mice to generate antibodies, we do it repeatedly over a number of weeks, and the antibody titer increases, and the antibodies being produced increase in affinity as the B-cells undergo somatic mutation, affinity maturation, and class switching. |
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