A bit over a year ago a long thread started on the Randonneuring forum on tubeless tires, thus oriented towards long distance pavement riding. There was a lot of information there from people with a lot of experience using tubeless on pavement. That is here:
https://www.bikeforums.net/long-dist...oad-tires.html
I have never used tubeless tires and have no plans to do so. But if I was going to do a tour in thorn country on normal touring width tires (if there is such a thing as normal touring width any more), I would consider sealant in tubes, or the prefilled sealant tubes from Slime. If there is a reason why this would be a bad idea, if some of you have used sealant in tubes on tires in the 32 to 37mm range, I would like to hear it.
I used tube sealant on a mountain biking trip a few years ago, car camping for a week and riding on mountain biking trails. I did not have any punctures from thorns.