It is very difficult to make bike components work in ways other than the way they are meant to. Front shifters are made to be on the left hand bars, and do not easily move to the right side. If the goal of the flat-bars is to sit up a little, then the stem will need to be shorter than the one that is OEM. Not a deal-breaker, maybe, but it hasn't been thought of as far as I can see. And probably not other things as well.Like the cost. A 1x drivetrain, even a cheapo, is a couple hundred. New brakes, similar, it's a big investment with no net increase in performance. And ... and ... this is without considering the realities of controlling a bicycle out in the real world with limited motion on one side! That is huge. There is a big difference in not having full ambidexterity because of limb loss, or congenital abnormality and the loss caused by central nervous system attrition. Before spending money on modifications, or (my recommendation), a proper hybrid style road bike, the o.p. is advised to take an unmodified bike for a test ride as proof of concept that riding single track is doable. If not, there are upright style three wheel and recumbent style three wheel bikes (trikes) that should be considered as a very good idea. FWIW.