+1 on teh "Strutz" from WalMart - someone at my work gave me a set and they are helping a lot.
I would also like to say that pedaling style can help or hinder hotspots as well. Pulling up, pushing down, lightening up on your gearing and spinning more can all change the way the foot is compressed and uncompressed. I think of these hotspots as the foot version of "white knuckling" it.