There's pretty much always a trade off between comfort, speed and cost, in that you can generally only have 2 of them.
Drop bars feel very twitchy compared to flat bars, but you get used to it pretty quickly. They do let you go a bit faster and give you more hand positions but they also result in you being more bent over.
Generally, smaller, smoother tyres will mean you'll feel the road harshness more (because they require a higher pressure to compensate for the reduced volume), but even going from a standard 25/28mm (at ~100psi) road tyre to 32mm (at ~80psi) will be a bit more comfortable without any notable reduction in speed.
However, if the issue is just about sweat on arrival to work, the solution is either to get better cycling clothing that wicks it away and/or just cycle a bit slower to avoid getting sweaty.