The camaraderie of meeting other riders along the way won't be there or will be very minimal this year. You will likely face many closed resources. You certainly will face less open and welcoming local folks along the way and likely will even face hostility that isn't usually there. All of those are major disadvantages of going this year without even thinking of any personal risks. It definitely isn't the best year to be planning a coast to coast trip.
I guess some may choose to go anyway, perhaps because they are not working and it is the one time in their life that has been the case. If you go I hope you have a great trip, but if going in a year or maybe two is an option that would be my choice and that is definitely not something I'd have ever said in the past.