One of my bikes has 406-32 front and 559-40 rear tires. I’m ok with different sizes on a bike - all the bikes I ride have 20” front and 26” rear wheels. Keep in mind there may be a touch of what seems like OCD playing into matching tires or having QR levers on the same side, etc.
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Bacchetta Giro A20, RANS V-Rex, RANS Screamer