Here's the Amazon e-cargo bike delivery that I've seen frequently since spring:
The trailer that gets towed behind is the main cargo hold.
I doubt any drainage cover would swallow the wheels on it, even my cargo e-bike has 3" wide tires that can easily ride over drainage grate gaps in NYC.
They seem to take up as much space as a car, if not more.
I don't know if they would get stuck in bumper-to-bumper traffic; that seems to defeat the purpose of reducing congestion, but at least reduces pollution.