Originally Posted by GhostRider62

NMN is much "cheaper" than Tru Noagen's nicotinamide riboside (NR) and being one step closer to the ultimate target....SIRT 1-?, it is reportedly much more effective. It works much better than NR in my experience. $145 for 100 grams of powder lasting 3-12 months is not cheap but I spend five times that on vintage white teas. I am reading HMB with interest. Thanks for sharing that.

You mentioned many times that you have had two singular times in your aging where your athletic performance dropped precipitously. I started to have problems at about age 60. My skin quality was changing visibly and my Dermatologist's knife was becoming a friend. Some of my labs were not good. Long story short, sleep studies revealed a couple of eye openers. One of significance here was a complete lack of deep sleep. None. It is thought that the endocrine system releases critical hormones such as HGH during these deep sleep phases. My sleep was horrible. One thing I did to combat it was a whey powder shake in the afternoon along with a nap. It helped recovery a little. I have recently started taking a couple of new supplements including NMN and my sleep has not been this good in a decade. I actually went out for a ride in 35F rain.....have not figured the motivation out but it seems significant. Aging and vitality or lack thereof seem to go hand in hand. I cannot say one way or the other why I seem to be improving, but obviously sleep is critical to athletic performance. I see NMN as a fancy B3 vitamin but I do agree that there needs to be more clinical trials and studies and caution with any supplement is warranted. Me? I'm taking it.

https://jamanetwork.com/journals/jam...article/192981

https://www.nmn.com/news/nad-and-the-sleep-wake-cycle

https://nmnbio.co.uk/blogs/news/inso...-sleep-a-treat

https://thesleepdoctor.com/2019/09/2...hm-supplement/