I am 230 lbs, ride 28's on the road at 80 psi front and 90 psi rear and have not had a flat in 2 years. I use tubes with Continental Ultra Sport tires. On the mountain bike I have never had a flat and have been mountain bike racing and trail riding since 1983. If you are experiencing a high rate of punctures from debris or have the need to run seriously low tire pressures, try tubeless.
It is more technical and requires topping off tire pressure before rides more frequently than tubes. Additional maintenance such as adding sealant at least once a year or dismounting and cleanout of tires and rims every two years puts it on par with tubes in my book. Since I do not have issues with flat tires, I have decided it is an unnecessary expense.