I have long distance toured on Gatorskins and liked them for the lively ride compared to the other tires folks toured on. The flat resistance is at least okay as is it the ride. I figure they are a compromise for that kind of riding.
Way back in the day I remember racing and training on a tire that I remember as being labeled Continental Grand Prix. I don't recall them having a number in the name, but I remember them as being great tires that I considered very expensive at the time.
Most of my tours are long enough that they pass through goat head thorn country at some point. I like a lively ride. I carry a very light load when touring these days using ultralight packing practices. Thoughts on a more lively model than the gatorskin, like the 4000 or 5000 and or tubeless, especially if there might be goatheads.