Sure-- happens to cars, too. A friend's daughter was in an accident as a passenger when they were waiting to turn left from a left-turn lane, crossing two lanes of traffic. One driver stopped and waved them across. The driver did not want to go, but the stopped driver was waving insistently. She goes... gets creamed by someone in the other lane-- and of course neither saw the other because of the person who stopped... luckily, no one was hurt badly. Friend's daughter was shaken up for a while, though. (Of course, if driving and the person in the other lane stops, probably best to look and see why... I always consider brake lights to be a "warning signal" when driving.)
I'm of the opinion that the "nicest" thing to do when driving/riding/walking is usually following the rules of the road and being predictable to others rather than making them second-guess or indeed be put in danger...